AdapterOcean/med_alpaca_standardized_cluster_92_std

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Please summerize the given abstract to a title	instruction	0	77,353	92	231,649
COVID-19 and gynecological cancers: Asia and Oceania Federation of Obstetrics and Gynecology oncology committee opinion	output	1	77,353	92	231,650
Since the outbreak of COVID-19, there have already been over 26 million people being infected and it is expected that the pandemic will not end in near future. Not only the daily activities and lifestyles of individuals have been affected, the medical practice has also been modified to cope with this emergency catastrophe. In particular, the cancer services have faced an unprecedented challenge. While the services may have been cut by the national authorities or hospitals due to shortage of manpower and resources, the medical need of cancer patients has increased. Cancer patients who are receiving active treatment may develop various kinds of complications especially immunosuppression from chemotherapy, and they and their carers will need additional protection against COVID-19. Besides, there is also evidence that cancer patients are more prone to deteriorate from COVID-19 if they contract the viral infection. Therefore, it is crucial to establish guidelines so that healthcare providers can triage their resources to take care of the most needed patients, reduce less important hospitalization and visit, and to avoid potential complications from treatment. The Asia and Oceania Federation of Obstetrics and Gynecology (AOFOG) hereby issued this opinion statement on the management of gynecological cancer patients during the COVID-19.	input	2	77,353	92	231,651
Please summerize the given abstract to a title	instruction	0	77,375	92	231,715
Emergent and urgent otologic surgeries during the SARS-CoV-2 pandemic: a protocol and review of literature	output	1	77,375	92	231,716
OBJECTIVE: To review guidelines for otologic procedures during the SARS-CoV-2 pandemic and to present a protocol for emergent or urgent mastoidectomy at our institution. DATA SOURCES: Guidelines regarding emergent and urgent otologic procedures from otolaryngologic societies are reviewed. We described a protocol for emergent or urgent mastoidectomy at our institution. CONCLUSION: Patients requiring urgent or emergent mastoidectomy during the COVID-19 pandemic require prompt treatment. We make the following recommendations: Emergent or urgent otologic procedures should be performed in a contained environment, such as a tent created by the microscope drape. The surgical team should practice using instruments in the tent setup to prepare for real cases. Otologic procedures should adhere to guidelines set for high-risk procedures.	input	2	77,375	92	231,717
Please summerize the given abstract to a title	instruction	0	77,414	92	231,832
A new frontier: Navigating hospital pharmacy practice during the covid-19 pandemic	output	1	77,414	92	231,833
The novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), first manifested in Wuhan, China in December 2019 as multiple cases of pneumonia with unknown etiology. This was the herald of an infectious catastrophe that would eventually affect millions of people across the world, claim countless lives, and uproot the very foundations of modern-day healthcare practice. Hospital pharmacists, alongside with physicians, nurses, and numerous other disciplines, are an integral part of the healthcare team that responded to this pandemic. The purpose of this article is to highlight the teamwork, determination, and innovativeness demonstrated by clinical pharmacists at a 510-bed community hospital in response to the coronavirus disease of 2019 (COVID-19). Pharmacists rose to the occasion to ensure that patients continue to receive the best therapy possible during this pandemic, and they supported other disciplines to ensure a collaborative response. Despite the unprecedented challenges posed to hospital pharmacy practice in the setting of COVID-19, our pharmacy team’s response has resoundingly proven the resiliency of the human spirit, and shows that nothing is insurmountable in the face of collaboration, creativity, and an overwhelming desire to care for our community. © 2021 Marmara University Press.	input	2	77,414	92	231,834
Please summerize the given abstract to a title	instruction	0	77,424	92	231,862
Paediatric Liver Transplantation During COVID-19 Pandemic: Lessons Learned and Unanswered Questions	output	1	77,424	92	231,863
COVID-19 pandemic has imposed many challenges on paediatric liver transplantation (PLT) services and has necessitated several adaptations in different stages of the process to ensure transplant centres can still deliver the proposed services in addition to protecting patients and staff against infection. This review article digs through the current literature to clarify the challenges imposed by SARS-CoV2 on PLT centres globally. It provides an overview of current practice as well as suggestions from experts in the field to overcome multiple obstacles. In paediatrics, the reaction to SARS-CoV2 may be less severe than that seen in the adult population, but this can change in view of newly discovered virus strains. Response of transplant centres to the current pandemic was variable depending on the anticipated risk and available resources. Telemedicine has helped PLT programmes to continue their activities while protecting patients, as well as staff against the risk of SARS-CoV2 virus. Further studies are needed to guide immunosuppression management in post-transplant infected candidates; answering this critical question will help PLT centres solve this dilemma.	input	2	77,424	92	231,864
Please summerize the given abstract to a title	instruction	0	77,479	92	232,027
Allergic Fungal Sinusitis: Ophthalmic Complications Due to the COVID-19 Pandemic and the Potential of Telemedicine	output	1	77,479	92	232,028
We report a case of a 26-year-old female who initially presented to an outside optometrist with complaints of proptosis and decreased visual acuity. Magnetic resonance imaging (MRI) obtained at that time was concerning for allergic fungal sinusitis. Unfortunately, the patient’s referral to ophthalmology was delayed due to the coronavirus disease 2019 (COVID-19) pandemic. On presentation to ophthalmology one year later, the patient had clinically deteriorated with significant visual and olfactory loss. She underwent emergent endoscopic sinus surgery by otolaryngology with histological analysis of the sinus debris confirming allergic fungal sinusitis. This is a unique case demonstrating the devastating impact that the COVID-19 pandemic had on patient care for an otherwise treatable condition. We propose the utilization of telemedicine networks as a way to prevent similar complications.	input	2	77,479	92	232,029
Please summerize the given abstract to a title	instruction	0	77,493	92	232,069
The impact of the COVID-19 pandemic on the field of pediatric rheumatology	output	1	77,493	92	232,070
The purpose of this review is to discuss the clinical management of children with pediatric rheumatic disease (PRD) during the Coronavirus disease of 2019 (COVID-19) pandemic, as well as the unique role of the pediatric rheumatologist during a time of emerging post-COVID inflammatory sequelae including, multisystem inflammatory syndrome in children (MIS-C). RECENT FINDINGS: To date, there has been little evidence to suggest that children with PRD, including those on immunomodulatory therapies, are at increased risk for severe COVID-19. Clinical guidance statements have been created to support clinical providers in providing care to children with PRD during the COVID-19 pandemic. Pediatric rheumatologists have also been called upon to assist in the identification and management of post-COVID sequelae, including the rapidly emerging inflammatory illness, MIS-C. SUMMARY: The COVID-19 era has been defined by a rapid expansion in scientific knowledge and a time of extraordinary local and worldwide collaboration, both within the pediatric rheumatology community, as well as across multiple disciplines. Through collective efforts, we have learned that children with PRD, including those on immunomodulatory therapies, are not at increased risk for severe COVID-19. Pediatric rheumatologists have also worked alongside other disciplines to develop guidance for the management of MIS-C, with the majority of patients experiencing excellent clinical outcomes.	input	2	77,493	92	232,071
Please summerize the given abstract to a title	instruction	0	77,629	92	232,477
COVID-19 and ECT - a Victorian perspective	output	1	77,629	92	232,478
OBJECTIVES: (i) to describe the operational strategies implemented to practise electroconvulsive therapy (ECT) safely, and (ii) to explore the effect of the lockdown and operational strategies on the characteristics of patients who received ECT during the initial 6 months of the COVID-19 lockdown. METHODS: At first, the operational strategies that were implemented at the Broadmeadows ECT suite were summarised. Subsequently, the characteristics of patients who received ECT in the lockdown period (16 March-16 September 2020) and in the comparison period (16 March-16 September 2019) were compared. RESULTS: Many safety measures were implemented, and there was no COVID-19 infection among mental health staff and patients. In the lockdown period, the number of patients (23.9%) and the total number of ECTs (29.4%) were less. This pattern was more prominent among the aged patients. CONCLUSION: Safe practices are essential to provide ECT during lockdowns even when the community transmission of COVID-19 is high.	input	2	77,629	92	232,479
Please summerize the given abstract to a title	instruction	0	77,655	92	232,555
SARS-CoV-2 – Wie kann und muss sich medizinisches Personal schützen?	output	1	77,655	92	232,556
The SARS-CoV‑2 pandemic represents a great challenge worldwide not only under the aspect of treatment but also of prevention. The infection curve could be flattened by the rapid implementation of simple distance and hygiene measures. In order to ensure current and future patient care in conjunction with protection of medical personnel working in the healthcare system during this pandemic, adequate protective equipment is essential. Routine care can only be resumed if there is sufficient and adequate personal protective equipment (PPE). If recommended hygiene protective measures including the necessary PPE are seriously taken into account both elective interventions and emergency care can be carried out without an increased risk of infection. This is very important in vascular surgery with a high proportion of urgent and emergency disease management.	input	2	77,655	92	232,557
Please summerize the given abstract to a title	instruction	0	77,667	92	232,591
Good practices recommendations from the Brazilian Society of Nephrology to Peritoneal Dialysis Services related to the new coronavirus (Covid-19) epidemic	output	1	77,667	92	232,592
Considering the new coronavirus epidemic (Covid-19), the Brazilian Society of Nephrology, represented by the Peritoneal Steering Committee, in agreement with the and the Dialysis Department, developed a series of recommendations for good clinical practices for peritoneal dialysis (PD) clinics, to be considered during the period of the Covid-19 epidemic. We aim to minimize the disease spread, protecting patients and staff, and ensuring the quality of the treatment provided and adequate follow-up for PD patients. The recommendations suggested at this moment must be adapted to each clinic’s reality and the conditions of the structural and human resources, dependent on the adequate financial provision of the public health system for its full implementation.	input	2	77,667	92	232,593
Please summerize the given abstract to a title	instruction	0	77,781	92	232,933
Surgical Management of Localized Hepatocellular Carcinoma in Times of Crisis: A Strategic Approach to Resource Utilization	output	1	77,781	92	232,934
The management of localized hepatocellular carcinoma (HCC) is complex and requires multidisciplinary consideration In times of crisis when resources are limited and the health of patients might be compromised, as is the case with COVID-19, a strategic approach that takes into account tumor characteristics, patient factors, and available treatment options can optimize patient outcomes while balancing resource utilization Herein, we detail our group's management strategy for patients with localized HCC during the global pandemic that carefully considers individual patient needs and those of the institutional workforce, the local healthcare system, and the greater patient community we serve	input	2	77,781	92	232,935
Please summerize the given abstract to a title	instruction	0	77,905	92	233,305
Anesthesiologist behavior and anesthesia machine use in the operating room during the COVID-19 pandemic: awareness and changes to cope with the risk of infection transmission	output	1	77,905	92	233,306
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) disease [coronavirus disease 2019 (COVID-19) infection] first appeared in December 2019 in China and is now spreading worldwide. Because SARS-CoV-2 can be transmitted via aerosols and surface contaminations of the environment, appropriate use of anesthesia machines and appropriate behavior in the operation room (OR) are required specifically in relation to this disease. The use of high-performance hydrophobic filters with a high rate of virus rejection is recommended as the type of viral filter, and surgical team behaviors that result in aerosol splashes should be avoided. Appropriate hand hygiene by the anesthesiologist is crucial to prevent unexpected environmental contamination. When the anesthesia machine is used instead of an intensive care unit ventilator, it is important to keep the fresh gas flow at least equal to the minute ventilation to prevent excessive humidity in the circuit and to monitor condensation in the circuit and inspiratory carbon dioxide pressure. In addition, both the surgical smoke inherent in thermal tissue destruction and the surgical team's shoe soles may be factors for the presence of SARS-CoV-2 in the operating room. Ensuring social distancing-even with a mask in the OR-may be beneficial because healthcare providers may be asymptomatic carriers. After the acute crisis period of COVID-19, the number of cases of essential but nonurgent surgeries for waiting patients is likely to increase; therefore, optimization of OR scheduling will be an important topic. Anesthesiologists will benefit from new standard practices focusing on the prevention of COVID-19 infection.	input	2	77,905	92	233,307
Please summerize the given abstract to a title	instruction	0	77,956	92	233,458
Management of cardiac patients in epidemic outbreak	output	1	77,956	92	233,459
In times of Covid19 epidemic/pandemic, cardiac patients are vulnerable group with many specific conditions that could aggravate their condition. In this narrative review, we present possible measures adequate in managing cardiac patients in epidemic outbreak. The overview on role of cardiologists and Crisis Management Team in management of cardiac patients is given. Protocols and measures implemented in Covid19 crises are presented in light of risk assessment and disease prevention of cardiac patients and measures that should be taken for each cardiac condition. Specificity of epidemics calls for specific measures in addressing cardiac patients as part of the affected population. Many possible outcomes could be expected in an epidemic outbreak in relation to cardiovascular diseases, but tailored measures will keep cardiac patients safe. Proposed preventive measures for cardiac patients could be implemented in existing protocols for epidemic outbreak.	input	2	77,956	92	233,460
Please summerize the given abstract to a title	instruction	0	77,964	92	233,482
Perspectives in surgical and anaesthetic management of lung cancer in the era of coronavirus disease 2019 (COVID-19)	output	1	77,964	92	233,483
Early in 2020, coronavirus disease 2019 (COVID-19) quickly spread globally, giving rise to a pandemic. In this critical scenario, patients with lung cancer need to continue to receive optimal care and at the same be shielded from infection with the potentially severe acute respiratory syndrome coronavirus 2. Upgrades to the prevention and control of infection have become paramount in order to lower the risk of hospital contagion. Aerosol-generating procedures such as endotracheal intubation or endoscopic procedures may expose health care workers to a high risk of infection. Moreover, thoracic anaesthesia usually requires highly complex airway management procedures because of the need for one-lung isolation and one-lung ventilation. Therefore, in the current pandemic, providing a fast-track algorithm for scientifically standardized diagnostic criteria and treatment recommendations for patients with lung cancer is urgent. Suggestions for improving existing contagion control guidelines are needed, even in the case of non-symptomatic patients who possibly are responsible for virus spread. A COVID-19-specific intraoperative management strategy designed to reduce risk of infection in both health care workers and patients is also required.	input	2	77,964	92	233,484
Please summerize the given abstract to a title	instruction	0	78,150	92	234,040
Care of patients with pulmonary arterial hypertension during the coronavirus (COVID-19) pandemic	output	1	78,150	92	234,041
The COVID-19 pandemic presents many unique challenges when caring for patients with pulmonary hypertension. The COVID-19 pandemic has altered routine standard of care practice and the acute management particularly for those patients with pulmonary arterial hypertension, where pulmonary arterial hypertension-specific treatments are used. It is important to balance the ongoing care and evaluation of pulmonary arterial hypertension patients with “exposure risk” to COVID-19 for patients coming to clinic or the hospital. If there is a morbidity and mortality benefit from starting pulmonary arterial hypertension therapies, for example in a patient with high-likelihood of pulmonary arterial hypertension, then it remains important to complete the thorough evaluation. However, the COVID-19 outbreak may also represent a unique time when pulmonary hypertension experts have to weigh the risks and benefits of the diagnostic work-up including potential exposure to COVID-19 versus initiating targeted pulmonary arterial hypertension therapy in a select high-risk, high likelihood World Symposium Pulmonary Hypertension Group 1 pulmonary arterial hypertension patients. This document will highlight some of the issues facing providers, patients, and the pulmonary arterial hypertension community in real-time as the COVID-19 pandemic is evolving and is intended to share expected common clinical scenarios and best clinical practices to help the community at-large.	input	2	78,150	92	234,042
Please summerize the given abstract to a title	instruction	0	78,184	92	234,142
Management of transplant patients outside hospital during COVID-19 epidemic: A Chinese experience	output	1	78,184	92	234,143
Coronavirus disease 2019 (COVID-19) pandemic poses an increasing challenge for transplant community. Aggressive management measures are conductive to improve compliance and to lower the risk of intra-hospital infection. In this Personal Viewpoint essay, we shared experiences about management strategies of transplant patients outside hospital amid the epidemic. With the aid of Cloud Clinic service and telemedicine care, transplant patients could be regularly followed up and get medical consultation online. Furthermore, personal health education and mental health assistance are enrolled in our practice.	input	2	78,184	92	234,144
Please summerize the given abstract to a title	instruction	0	78,186	92	234,148
Consensus Statement on Coronary Intervention during the Coronavirus Disease 2019 (COVID-19) Pandemic: from the Korean Society of Interventional Cardiology (KSIC)	output	1	78,186	92	234,149
Coronavirus disease 2019 (COVID-19) is a highly contagious disease caused by the novel virus severe acute respiratory syndrome coronavirus-2. The first case developed in December, 2019 in Wuhan, China; several months later, COVID-19 has become pandemic, and there is no end in sight. This disaster is also causing serious health problems in the area of cardiovascular intervention. In response, the Korean Society of Interventional Cardiology formed a COVID-19 task force to develop practice guidelines. This special article introduces clinical practice guidelines to prevent secondary transmission of COVID-19 within facilities; the guidelines were developed to protect patients and healthcare workers from this highly contagious virus. We hope these guidelines help healthcare workers and cardiovascular disease patients around the world cope with the COVID-19 pandemic.	input	2	78,186	92	234,150
Please summerize the given abstract to a title	instruction	0	78,209	92	234,217
Lessons Learned and Experiences Shared From the Front Lines: Milan and Madrid.	output	1	78,209	92	234,218
Under the aegis of the American College of Surgeons (ACS), the senior author (SDW), a member of the Board of Regents of the ACS, interviewed 3 of his international colleagues in colon and rectal surgery who found themselves dealing with a flood of patients from the COVID-19 pandemic. Each was in a "hot spot" where the outbreak overwhelmed the capacities of the hospitals. Professor Antonino Spinelli of Milan dealt with the sudden increase in COVID-19 patients that threatened to push all other emergencies and urgent cancer cases aside. Providers lacked the personal protective equipment to be adequately safe in the environment. In Madrid, Dr Julio Mayol recounted how 10%-15% of the workers in his hospital were incapacitated by the virus, many of them doctors providing direct care to patients. The disease is so prevalent that all emergency patients are treated as though they have the infection. Having practices in Saudi Arabia and Spain, Dr Delia Cortés-Guiral saw how the former country controlled the epidemic through a strict lockdown of travel and closure of holy pilgrimage sites and social gatherings. In contrast, upon her return to her native country, she experienced the near-breakdown of the health care system by the suddenness of the outbreak. "There are now no specialists now, she says." All of the specialties are treating COVID-19 patients and all of us are learning at the same time how to deal with this disease."It is a nightmare now here in Spain".	input	2	78,209	92	234,219
Please summerize the given abstract to a title	instruction	0	78,291	92	234,463
Home Care for Cancer Patients During COVID-19 Pandemic: The Double Triage Protocol	output	1	78,291	92	234,464
Abstract Patients with cancer have an increased risk of developing severe forms of coronavirus disease 2019, and patients with advanced cancer who are followed at home represent a particularly frail population. Although with substantial differences, the challenges that cancer care professionals have to face during a pandemic are quite similar to those posed by natural disasters. We have already managed the oncological home care service in L’Aquila (middle Italy) after the 2009 earthquake. With this letter, we want to share the procedures and tools that we have started using at the home care service of the Tuscany Tumor Association during the coronavirus disease 2019 pandemic.	input	2	78,291	92	234,465
Please summerize the given abstract to a title	instruction	0	78,343	92	234,619
Recommendations for Safe Dental Care: A Systematic Review of Clinical Practice Guidelines in the First Year of the COVID-19 Pandemic	output	1	78,343	92	234,620
In the context of a pandemic, the rapid development of clinical practice guidelines (CPGs) is critical to guide dental staff towards the safe provision of dental care; detailed knowledge of the recommendations will help to achieve the intended results. We carried out a systematic review of the recommendations in clinical practice guidelines (CPGs) on the provision of dental care issued during the first year of the COVID-19 pandemic. A systematic database search was performed in MEDLINE, EMBASE, LILACS, Epistemonikos, and Trip databases to identify documents with recommendations intended to minimize the risk of COVID-19 transmission during dental care. The selection process and data extraction were carried out by two researchers independently. The majority of CPGs recommended the use of rubber dam, high-volume evacuator, mouthwash prior to dental care, four-handed work, and mechanical barriers. The use of aerosol-generating equipment should be avoided whenever possible. In aerosol-generating procedures, the use of a N95 respirator (or similar) is recommended, in addition to a face protector, an impermeable disposable apron/gown, a cap, and gloves. The CPGs developed during the first year of the pandemic offer recommendations which guide dental staff in providing safe dental care, minimizing exposure to SARS-CoV-2 and reducing the risk of COVID-19 infection in the clinical environment. Such recommendations must, however, be updated as new evidence arises.	input	2	78,343	92	234,621
Please summerize the given abstract to a title	instruction	0	78,356	92	234,658
Cardiothoracic Surgery during COVID-19: Our Experience with Different Strategies	output	1	78,356	92	234,659
BACKGROUND: An acute respiratory disease (COVID-19), caused by a novel coronavirus (SARS-CoV-2,), has been declared a pandemic by WHO. A surgery on COVID-19 patients not only involves a risk of spread of the disease but also there is a serious concern for the patient's surgical outcomes and resources requirement. AIM: The retrospective study is aimed to provide a protocol for pre-operative testing of SARS CoV-2 using RT-PCR in the patient undergoing cardio-thoracic surgeries. MATERIAL AND METHODS: To analyze the impact of pre-operative testing of SARS- CoV-2 using RT-PCR in the patient undergoing elective cardio-thoracic surgeries. The patient who underwent surgical interventions during the COVID-19 lockdown period was divided into two phases. Phase I (without COVID-19 RT-PCR testing) and Phase II (with pre-operative COVID-19 RT-PCR testing). The retrospective comparison between the two study groups was done using Student t-test, Mann–Whitney U, and Chi square (χ(2)) test depending upon the clinical variable to be analyzed. RESULTS: During the early phase (phase I), 26 patients underwent cardio-thoracic surgery without COVID-19 RT-PCR test. Whereas, during phase II, all patients were tested for COVID-19 using RT-PCR, preoperatively and a total of 64 surgeries were performed during this phase. One patient planned for CABG was positive on RT-PCR for COVID-19 and was sent to the quarantine ward. The difference in the pre-operative hospital stay between two groups was found to be statistically significant and a significant decrease in the number of PPE kits used, during the phase I. CONCLUSION: All asymptomatic patients should be tested for COVID-19 using RT-PCR prior to cardio-thoracic surgeries not only to contain the disease but to avoid potential implications of COVID-19 on the perioperative course, without added financial implications.	input	2	78,356	92	234,660
Please summerize the given abstract to a title	instruction	0	78,367	92	234,691
Solid organ transplantation in the era of COVID-19: lessons from the past six months	output	1	78,367	92	234,692
COVID-19 outbreak has significantly upended solid organ transplant (SOT) practice around the world. Early reports confirmed the heavy burden of COVID-19 in SOT recipients with mortality rates reaching up to 35%. Because most transplant recipients harbored multiple comorbidities known to be associated with a severe course of COVID-19, the true impact of immunosuppression by itself remained an unsolved issue. Transplant societies have initially recommended to postpone non urgent renal transplantations, while trying to maintain life-saving transplant programs, such as heart, lung and liver transplantations. The pandemic thus resulted in an unprecedented and sudden drop of transplant activity worldwide. Moreover, the best treatment strategy in infected patients was challenging. Both reduction of immunosuppression and use of targeted therapies aiming at counteracting SARS-CoV-2 infection were the two faces of the therapeutic armamentarium. Recent controlled studies have better delineated the basis of mitigating and management strategies to improve patients' outcome. Nevertheless, and given the persistence of circulating virus, evidence-based recommendations in SOT recipients remain unclear. The resumption of transplant activity should be tailored with careful selection of both donors and recipients. Transplant decision should be made on a case-by-case basis after thorough assessment of the risks and benefits.	input	2	78,367	92	234,693
Please summerize the given abstract to a title	instruction	0	78,385	92	234,745
Thoracic Surgeons’ Insights: Improving Thoracic Surgery Outcomes During the Coronavirus Disease 2019 Pandemic	output	1	78,385	92	234,746
[Figure: see text]	input	2	78,385	92	234,747
Please summerize the given abstract to a title	instruction	0	78,414	92	234,832
Clinical strategies for optimizing infusion center care through a pandemic.	output	1	78,414	92	234,833
The national pandemic resulting from the novel coronavirus, COVID-19, has made the delivery of care for patients with cancer a challenge. There are competing risks of mortality from cancer versus serious complications and higher risk of death from COVID-19 in immunocompromised hosts. Furthermore, compounding these concerns is the inadequate supply of personal protective equipment, decreased hospital capacity, and paucity of effective treatments or vaccines to date for COVID-19. Guidance measures and recommendations have been published by national organizations aiming to facilitate the delivery of care in a safe and effective manner, many of which, are permanently adoptable interventions. Given the critical importance to continue chemotherapy, there remains additional interventions to further enhance patient safety while conserving healthcare resources such as adjustments in medication administration, reduction in laboratory or drug monitoring, and home delivery of specialty infusions. In this manuscript, we outline how to implement these actionable interventions of chemotherapy and supportive care delivery to further enhance the current precautionary measures while maintaining safe and effective patient care. Coupled with current published standards, these strategies can help alleviate the numerous challenges associated with this pandemic.	input	2	78,414	92	234,834
Please summerize the given abstract to a title	instruction	0	78,550	92	235,240
Mount Sinai NY Surgeon on the Front Lines of the COVID-19 Pandemic in Brooklyn, NY, USA.	output	1	78,550	92	235,241
A surgeon was among the teams caring for critically-ill patients with COVID-19 infection during the height of the pandemic in March and April 2020 in Brooklyn. He recorded his experiences and thoughts as events unfolded, a chronicle of the landmark public health event of the century. Working to exhaustion alongside his colleagues from Mount Sinai Hospital, he encountered tragedy and inspiration.	input	2	78,550	92	235,242
Please summerize the given abstract to a title	instruction	0	78,588	92	235,354
Increased photokeratitis during the coronavirus disease 2019 pandemic: Clinical and epidemiological features and preventive measures	output	1	78,588	92	235,355
An increased incidence of photokeratitis has occurred during the coronavirus disease 2019 (COVID-19) pandemic due to improper and unprotected use of ultraviolet lamps. Here, we summarize the clinical and epidemiological features of this increased incidence of photokeratitis and share advice in using health education to prevent it. We collected data from patients diagnosed with photokeratitis from October 7, 2019 to December 1, 2019, and from February 17, 2020 to April 12, 2020, and compared the frequency of onset, site of ultraviolet radiation (UVR) exposure, reason for exposure, exposure time, and recovery time. We also implemented and evaluated multiple measures of public health education to prevent increased disease. After the COVID-19 outbreak, the frequency of onset of photokeratitis increased significantly, especially among young women. The main reason for UVR exposure changed from welding to disinfection. The incidence sites varied, and the exposure time was longer. As a result, patients needed a longer time to recover. Positive health education was an useful and convenient measure to prevent the disease. While the COVID-19 pandemic is ongoing, more attention should be paid to public health and implement positive measures to prevent photokeratitis.	input	2	78,588	92	235,356
Please summerize the given abstract to a title	instruction	0	78,718	92	235,744
New Vision for a Patient with Diabetes and Retinal Migraines	output	1	78,718	92	235,745
Retinal migraine is a chronic, disabling headache disorder that strikes sufferers with recurrent, transient episodes of monocular vision loss before the onset of a throbbing headache on the same side as the visual disturbance The author discusses the experience of a patient with type 2 diabetes perceiving these frightening episodes of transient visual disturbances during the coronavirus disease 2019 pandemic in which stressors and missed meals precipitated and exacerbated these attacks With an increased understanding of the characteristics of retinal migraines, nurse practitioners can work closely with other health care professionals to provide comprehensive and patient-centered care to these individuals	input	2	78,718	92	235,746
Please summerize the given abstract to a title	instruction	0	78,748	92	235,834
Pandemics and Pediatric Otolaryngology	output	1	78,748	92	235,835
OBJECTIVE: To describe how the COVID pandemic changed the epidemiology and management of pediatric otolaryngologic diseases, which may influence clinical decision-making in the future. FINDINGS: Many changes were made to the structure of healthcare delivery to minimize transmission of coronavirus. As a result, there was a widespread adoption of telehealth. Additionally, guidelines were published with new protocols for evaluation and management of common pediatric otolaryngologic conditions, which in many circumstances, delayed or replaced surgical intervention. Now, as we evaluate the impact of these clinical changes, we have gained new understanding about the pathophysiology of certain pediatric conditions, namely otitis media, for which upper respiratory infection (URI) exposure may play a larger role than previously thought. CONCLUSION: As we have altered practice patterns for common pediatric otolaryngologic conditions, we recognize that ongoing research may help us determine if surgical interventions have been overutilized in the past and help guide clinical practice guidelines moving forward.	input	2	78,748	92	235,836
Please summerize the given abstract to a title	instruction	0	78,790	92	235,960
Problems of care for STEMI patients in coronavirus pandemic	output	1	78,790	92	235,961
The covid-19 pandemic negatively affects time-dependent care and the course of STEMI in several aspects: Some patients delay seeking emergency care or even do not call it at all because of fear of contracting covid-19 at hospitals. The presentations of STEMI and covid-19 can overlap and mimic each other. Both conditions may coexist. Uncertainty regarding diagnosis may add to delays. Provider΄s concerns about the covid-19 infection or lack of cath lab staff may lead to changes in treatment algorhithms. There may also be delay due to the infection-control measures employed by medical staff. Reduction in non-covid care, overwhelmed emergency medical services and hospitals, staff-absences, and lack of beds may all lead to treatment delay or even inability to provide it. Inflammatory and prothrombotic states in patients with covid-19 increase the risk of developing STEMI as well as that of STEMI complications. Hypoxia due to covid-19 lung disease deepens myocardial ischemia during STEMI and may extend the volume of STEMI and increase the risk of heart failure. Covid myocarditis Conclusion: It is apparent that STEMI in covid-19 infected patients is not the same disease process as STEMI that without covid-19 infection. Patients with STEMI and covid-19 have a higher risk of heart failure, cardiac arrest, cardiogenic shock, greater intracoronary thrombosis and stent thrombosis, resulting in higher cardiac and non-cardiac mortality. Aggressive antithrombotic treatment is recommended. Even in the covid era it is essential to insist on timely treatment of STEMI. Training of cardiac catheterization personnel on how to use personal protective equipment as well as vaccination are crucial to limit the risk of acquiring infection. (English) [ABSTRACT FROM AUTHOR] Infekce covid-19 a covidová pandemie představují problém pro péči o nemocné se STEMI. Výskyt, průběh, léčbu a prognózu STEMI ovlivňuje covidová epidemie v několika aspektech: Část nemocných z obavy před covidovou nákazou v nemocnici oddaluje přivolání zdravotnické pomoci, nebo dokonce pomoc vůbec nezavolá. Příznaky STEMI a covid-19 se mohou překrývat a vzájemně napodobovat, navíc mohou koexistovat, nejistota při stanovení diagnózy může vést ke zpoždění léčby. Obava z covidové nákazy zdravotníků nebo nedostatek personálu katetrizačních laboratoří může vést ke změně léčebných algoritmů. Přetížené zdravotní služby, omezení „necovidové“ péče, chybějící personál, nedostatek lůžek mohou mít za následek prodlevu v léčbě STEMI až nemožnost léčbu poskytnout. Použítí ochranných prostředků proti šíření covid-19 může vést ke zpoždění léčby. Zánětlivý a protrombotický stav během covidové infekce zvyšuje riziko vzniku infarktu myokardu a zvyšuje riziko trombotických komplikací již probíhajícího STEMI. Hypoxie způsobená covidovým postižením plic prohlubuje ischemii myokardu při AIM, může zvětšit rozsah infarktu a zvyšuje riziko srdečního selhání při AIM. Covidová myokarditida. Závěr: STEMI u nemocného s covid-19 není stejná nemoc jako STEMI bez covid-19. Nemocní s covid-19 a STEMI mají častěji srdeční selhání a srdeční zástavu, rozsáhlejší intrakoronární trombózu, významně vyšší riziko akutní trombózy stentu, kardiogenního šoku po PCI a významně vyšší nemocniční kardiální i nekardiální mortalitu. Je indikována agresivnější antitrombotická léčba. I v covidové době je nutná maximální snaha o co nejrychlejší zajištění reperfuzní léčby a dodržení časových limitů pro její provedení. Velmi důležité jsou nácvik používání ochranných pomůcek proti šíření infekce a vakcinace. (Czech) [ABSTRACT FROM AUTHOR] Copyright of Intervencní a Akutní Kardiologie is the property of SOLEN sro and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)	input	2	78,790	92	235,962
Please summerize the given abstract to a title	instruction	0	79,136	92	236,998
Contradictory Responses to the COVID-19 Pandemic in Amyotrophic Lateral Sclerosis Patients and Their Families and Caregivers in Japan	output	1	79,136	92	236,999
Objective The coronavirus disease 2019 (COVID-19) pandemic has resulted in a shortage of medical resources, including ventilators, personal protective equipment, medical staff, and hospital beds. We investigated the impact of COVID-19 in amyotrophic lateral sclerosis (ALS) patients, their families, caregivers, and medical experts. Methods We conducted a nationwide ALS webinar about COVID-19 in May 2020 and sent a questionnaire to those enrolled. Results A total of 135 participants (31 ALS patients; 23 families and caregivers of ALS patients; 81 medical experts) responded to this cross-sectional self-report questionnaire. The results showed that tracheostomy and invasive ventilation (TIV) was used in 22.6% of ALS patients, whereas 77.4% of ALS patients were not under TIV. Among non-TIV patients (n=24), 79.2% did not want TIV in the future. However, 47.4% of non-TIV patients not wanting a tracheostomy in advanced stages replied that they would want an emergency tracheostomy if they developed COVID-19-related pneumonia. These results suggest that ALS patients may be receptive to emergency treatments for reasons other than ALS. In addition, approximately half of the ALS patients agreed with the policy of not ventilating the elderly or ALS patients in case of a ventilator shortage. Furthermore, compared with medical experts, few ALS patients reported that the chance for ALS patients to obtain work was higher due to the increasing availability of remote work. Conclusions This survey indicates that the COVID-19 pandemic might be associated with increased distress about access to care and work, inducing contradictory responses and potential hopelessness among ALS patients.	input	2	79,136	92	237,000
Please summerize the given abstract to a title	instruction	0	79,137	92	237,001
Enteral stoma care during COVID‐19 pandemic: practical advice	output	1	79,137	92	237,002
The COVID‐19 pandemic represents an enormous challenge for global health systems. Stoma care represents a potentially neglected component during the outbreak and no specific recommendations on stoma care have been published up till now. In this manuscript, MISSTO (Multidisciplinary Italian Study group for STOmas) provides practical advice on optimal enteral stoma care in adults during the COVID‐19 pandemic. Translations in four other languages (Spanish, Italian, Traditional Chinese, Simplified Chinese) are attached in the appendix to enable dissemination of the document worldwide.	input	2	79,137	92	237,003
Please summerize the given abstract to a title	instruction	0	79,138	92	237,004
Evidence-based management of COVID-19 in cancer patients: Guideline by the Infectious Diseases Working Party (AGIHO) of the German Society for Haematology and Medical Oncology (DGHO)	output	1	79,138	92	237,005
Since its first detection in China in late 2019 the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the associated infectious disease COVID-19 continue to have a major impact on global healthcare and clinical practice. Cancer patients, in particular those with haematological malignancies, seem to be at an increased risk for a severe course of infection. Deliberations to avoid or defer potentially immunosuppressive therapies in these patients need to be balanced against the overarching goal of providing optimal antineoplastic treatment. This poses a unique challenge to treating physicians. This guideline provides evidence-based recommendations regarding prevention, diagnostics and treatment of SARS-CoV-2 infection and COVID-19 as well as strategies towards safe antineoplastic care during the COVID-19 pandemic. It was prepared by the Infectious Diseases Working Party (AGIHO) of the German Society for Haematology and Medical Oncology (DGHO) by critically reviewing the currently available data on SARS-CoV-2 and COVID-19 in cancer patients applying evidence-based medicine criteria.	input	2	79,138	92	237,006
Please summerize the given abstract to a title	instruction	0	79,221	92	237,253
Safety guidelines for non-surgical facial procedures during covid-19 outbreak	output	1	79,221	92	237,254
BACKGROUND: The novel coronavirus (COVID-19) pandemic is expected to last for an extended time, making strict safety precautions for office procedures unavoidable. The lockdown is going to be lifted in many areas, and strict guidelines detailing the infection control measures for aesthetic clinics are going to be of particular importance. METHODS: A virtual meeting was conducted with the members (n=12) of the European Academy of Facial Plastic Surgery Focus Group to outline the safety protocol for the non-surgical facial aesthetic procedures for aesthetic practices in order to protect the clinic staff and the patients from SARS-CoV-2 infection. The data analysis was undertaken by thematic and iterative approach. RESULTS: Consensus guidelines for non-surgical facial aesthetic procedures based on current knowledge are provided for three levels: precautions before visiting the clinic, precautions during the clinic visit, and precautions after the clinic visit. CONCLUSIONS: Sound infection control measures are mandatory for non-surgical aesthetic practices all around the world. These may vary from country to country, but this logical approach can be customized according to the respective country laws and guidelines.	input	2	79,221	92	237,255
Please summerize the given abstract to a title	instruction	0	79,235	92	237,295
Our experiences of resuming services in ENT departments in Wuhan, once a COVID-19 epicenter	output	1	79,235	92	237,296
Abstract The pandemic of coronavirus disease 2019 (COVID-19) showed a significant impact on routine daily services in departments of otorhinolaryngology head and neck surgery. The city of Wuhan, as the first reported epicenter in the world, resumed medical service since April 8, 2020. As the biggest ENT services provider in Wuhan, we share out institution's triage and screening system in the resuming period.	input	2	79,235	92	237,297
Please summerize the given abstract to a title	instruction	0	79,263	92	237,379

Please summerize the given abstract to a title

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COVID-19 and gynecological cancers: Asia and Oceania Federation of Obstetrics and Gynecology oncology committee opinion

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Since the outbreak of COVID-19, there have already been over 26 million people being infected and it is expected that the pandemic will not end in near future. Not only the daily activities and lifestyles of individuals have been affected, the medical practice has also been modified to cope with this emergency catastrophe. In particular, the cancer services have faced an unprecedented challenge. While the services may have been cut by the national authorities or hospitals due to shortage of manpower and resources, the medical need of cancer patients has increased. Cancer patients who are receiving active treatment may develop various kinds of complications especially immunosuppression from chemotherapy, and they and their carers will need additional protection against COVID-19. Besides, there is also evidence that cancer patients are more prone to deteriorate from COVID-19 if they contract the viral infection. Therefore, it is crucial to establish guidelines so that healthcare providers can triage their resources to take care of the most needed patients, reduce less important hospitalization and visit, and to avoid potential complications from treatment. The Asia and Oceania Federation of Obstetrics and Gynecology (AOFOG) hereby issued this opinion statement on the management of gynecological cancer patients during the COVID-19.

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231,715

Emergent and urgent otologic surgeries during the SARS-CoV-2 pandemic: a protocol and review of literature

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OBJECTIVE: To review guidelines for otologic procedures during the SARS-CoV-2 pandemic and to present a protocol for emergent or urgent mastoidectomy at our institution. DATA SOURCES: Guidelines regarding emergent and urgent otologic procedures from otolaryngologic societies are reviewed. We described a protocol for emergent or urgent mastoidectomy at our institution. CONCLUSION: Patients requiring urgent or emergent mastoidectomy during the COVID-19 pandemic require prompt treatment. We make the following recommendations: Emergent or urgent otologic procedures should be performed in a contained environment, such as a tent created by the microscope drape. The surgical team should practice using instruments in the tent setup to prepare for real cases. Otologic procedures should adhere to guidelines set for high-risk procedures.

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231,832

A new frontier: Navigating hospital pharmacy practice during the covid-19 pandemic

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The novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), first manifested in Wuhan, China in December 2019 as multiple cases of pneumonia with unknown etiology. This was the herald of an infectious catastrophe that would eventually affect millions of people across the world, claim countless lives, and uproot the very foundations of modern-day healthcare practice. Hospital pharmacists, alongside with physicians, nurses, and numerous other disciplines, are an integral part of the healthcare team that responded to this pandemic. The purpose of this article is to highlight the teamwork, determination, and innovativeness demonstrated by clinical pharmacists at a 510-bed community hospital in response to the coronavirus disease of 2019 (COVID-19). Pharmacists rose to the occasion to ensure that patients continue to receive the best therapy possible during this pandemic, and they supported other disciplines to ensure a collaborative response. Despite the unprecedented challenges posed to hospital pharmacy practice in the setting of COVID-19, our pharmacy team’s response has resoundingly proven the resiliency of the human spirit, and shows that nothing is insurmountable in the face of collaboration, creativity, and an overwhelming desire to care for our community. © 2021 Marmara University Press.

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231,862

Paediatric Liver Transplantation During COVID-19 Pandemic: Lessons Learned and Unanswered Questions

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COVID-19 pandemic has imposed many challenges on paediatric liver transplantation (PLT) services and has necessitated several adaptations in different stages of the process to ensure transplant centres can still deliver the proposed services in addition to protecting patients and staff against infection. This review article digs through the current literature to clarify the challenges imposed by SARS-CoV2 on PLT centres globally. It provides an overview of current practice as well as suggestions from experts in the field to overcome multiple obstacles. In paediatrics, the reaction to SARS-CoV2 may be less severe than that seen in the adult population, but this can change in view of newly discovered virus strains. Response of transplant centres to the current pandemic was variable depending on the anticipated risk and available resources. Telemedicine has helped PLT programmes to continue their activities while protecting patients, as well as staff against the risk of SARS-CoV2 virus. Further studies are needed to guide immunosuppression management in post-transplant infected candidates; answering this critical question will help PLT centres solve this dilemma.

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231,864

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232,027

Allergic Fungal Sinusitis: Ophthalmic Complications Due to the COVID-19 Pandemic and the Potential of Telemedicine

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We report a case of a 26-year-old female who initially presented to an outside optometrist with complaints of proptosis and decreased visual acuity. Magnetic resonance imaging (MRI) obtained at that time was concerning for allergic fungal sinusitis. Unfortunately, the patient’s referral to ophthalmology was delayed due to the coronavirus disease 2019 (COVID-19) pandemic. On presentation to ophthalmology one year later, the patient had clinically deteriorated with significant visual and olfactory loss. She underwent emergent endoscopic sinus surgery by otolaryngology with histological analysis of the sinus debris confirming allergic fungal sinusitis. This is a unique case demonstrating the devastating impact that the COVID-19 pandemic had on patient care for an otherwise treatable condition. We propose the utilization of telemedicine networks as a way to prevent similar complications.

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The impact of the COVID-19 pandemic on the field of pediatric rheumatology

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The purpose of this review is to discuss the clinical management of children with pediatric rheumatic disease (PRD) during the Coronavirus disease of 2019 (COVID-19) pandemic, as well as the unique role of the pediatric rheumatologist during a time of emerging post-COVID inflammatory sequelae including, multisystem inflammatory syndrome in children (MIS-C). RECENT FINDINGS: To date, there has been little evidence to suggest that children with PRD, including those on immunomodulatory therapies, are at increased risk for severe COVID-19. Clinical guidance statements have been created to support clinical providers in providing care to children with PRD during the COVID-19 pandemic. Pediatric rheumatologists have also been called upon to assist in the identification and management of post-COVID sequelae, including the rapidly emerging inflammatory illness, MIS-C. SUMMARY: The COVID-19 era has been defined by a rapid expansion in scientific knowledge and a time of extraordinary local and worldwide collaboration, both within the pediatric rheumatology community, as well as across multiple disciplines. Through collective efforts, we have learned that children with PRD, including those on immunomodulatory therapies, are not at increased risk for severe COVID-19. Pediatric rheumatologists have also worked alongside other disciplines to develop guidance for the management of MIS-C, with the majority of patients experiencing excellent clinical outcomes.

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232,477

COVID-19 and ECT - a Victorian perspective

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OBJECTIVES: (i) to describe the operational strategies implemented to practise electroconvulsive therapy (ECT) safely, and (ii) to explore the effect of the lockdown and operational strategies on the characteristics of patients who received ECT during the initial 6 months of the COVID-19 lockdown. METHODS: At first, the operational strategies that were implemented at the Broadmeadows ECT suite were summarised. Subsequently, the characteristics of patients who received ECT in the lockdown period (16 March-16 September 2020) and in the comparison period (16 March-16 September 2019) were compared. RESULTS: Many safety measures were implemented, and there was no COVID-19 infection among mental health staff and patients. In the lockdown period, the number of patients (23.9%) and the total number of ECTs (29.4%) were less. This pattern was more prominent among the aged patients. CONCLUSION: Safe practices are essential to provide ECT during lockdowns even when the community transmission of COVID-19 is high.

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232,555

SARS-CoV-2 – Wie kann und muss sich medizinisches Personal schützen?

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The SARS-CoV‑2 pandemic represents a great challenge worldwide not only under the aspect of treatment but also of prevention. The infection curve could be flattened by the rapid implementation of simple distance and hygiene measures. In order to ensure current and future patient care in conjunction with protection of medical personnel working in the healthcare system during this pandemic, adequate protective equipment is essential. Routine care can only be resumed if there is sufficient and adequate personal protective equipment (PPE). If recommended hygiene protective measures including the necessary PPE are seriously taken into account both elective interventions and emergency care can be carried out without an increased risk of infection. This is very important in vascular surgery with a high proportion of urgent and emergency disease management.

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232,591

Good practices recommendations from the Brazilian Society of Nephrology to Peritoneal Dialysis Services related to the new coronavirus (Covid-19) epidemic

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Considering the new coronavirus epidemic (Covid-19), the Brazilian Society of Nephrology, represented by the Peritoneal Steering Committee, in agreement with the and the Dialysis Department, developed a series of recommendations for good clinical practices for peritoneal dialysis (PD) clinics, to be considered during the period of the Covid-19 epidemic. We aim to minimize the disease spread, protecting patients and staff, and ensuring the quality of the treatment provided and adequate follow-up for PD patients. The recommendations suggested at this moment must be adapted to each clinic’s reality and the conditions of the structural and human resources, dependent on the adequate financial provision of the public health system for its full implementation.

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232,593

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77,781

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232,933

Surgical Management of Localized Hepatocellular Carcinoma in Times of Crisis: A Strategic Approach to Resource Utilization

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The management of localized hepatocellular carcinoma (HCC) is complex and requires multidisciplinary consideration In times of crisis when resources are limited and the health of patients might be compromised, as is the case with COVID-19, a strategic approach that takes into account tumor characteristics, patient factors, and available treatment options can optimize patient outcomes while balancing resource utilization Herein, we detail our group's management strategy for patients with localized HCC during the global pandemic that carefully considers individual patient needs and those of the institutional workforce, the local healthcare system, and the greater patient community we serve

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233,305

Anesthesiologist behavior and anesthesia machine use in the operating room during the COVID-19 pandemic: awareness and changes to cope with the risk of infection transmission

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The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) disease [coronavirus disease 2019 (COVID-19) infection] first appeared in December 2019 in China and is now spreading worldwide. Because SARS-CoV-2 can be transmitted via aerosols and surface contaminations of the environment, appropriate use of anesthesia machines and appropriate behavior in the operation room (OR) are required specifically in relation to this disease. The use of high-performance hydrophobic filters with a high rate of virus rejection is recommended as the type of viral filter, and surgical team behaviors that result in aerosol splashes should be avoided. Appropriate hand hygiene by the anesthesiologist is crucial to prevent unexpected environmental contamination. When the anesthesia machine is used instead of an intensive care unit ventilator, it is important to keep the fresh gas flow at least equal to the minute ventilation to prevent excessive humidity in the circuit and to monitor condensation in the circuit and inspiratory carbon dioxide pressure. In addition, both the surgical smoke inherent in thermal tissue destruction and the surgical team's shoe soles may be factors for the presence of SARS-CoV-2 in the operating room. Ensuring social distancing-even with a mask in the OR-may be beneficial because healthcare providers may be asymptomatic carriers. After the acute crisis period of COVID-19, the number of cases of essential but nonurgent surgeries for waiting patients is likely to increase; therefore, optimization of OR scheduling will be an important topic. Anesthesiologists will benefit from new standard practices focusing on the prevention of COVID-19 infection.

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77,956

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Management of cardiac patients in epidemic outbreak

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In times of Covid19 epidemic/pandemic, cardiac patients are vulnerable group with many specific conditions that could aggravate their condition. In this narrative review, we present possible measures adequate in managing cardiac patients in epidemic outbreak. The overview on role of cardiologists and Crisis Management Team in management of cardiac patients is given. Protocols and measures implemented in Covid19 crises are presented in light of risk assessment and disease prevention of cardiac patients and measures that should be taken for each cardiac condition. Specificity of epidemics calls for specific measures in addressing cardiac patients as part of the affected population. Many possible outcomes could be expected in an epidemic outbreak in relation to cardiovascular diseases, but tailored measures will keep cardiac patients safe. Proposed preventive measures for cardiac patients could be implemented in existing protocols for epidemic outbreak.

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Perspectives in surgical and anaesthetic management of lung cancer in the era of coronavirus disease 2019 (COVID-19)

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Early in 2020, coronavirus disease 2019 (COVID-19) quickly spread globally, giving rise to a pandemic. In this critical scenario, patients with lung cancer need to continue to receive optimal care and at the same be shielded from infection with the potentially severe acute respiratory syndrome coronavirus 2. Upgrades to the prevention and control of infection have become paramount in order to lower the risk of hospital contagion. Aerosol-generating procedures such as endotracheal intubation or endoscopic procedures may expose health care workers to a high risk of infection. Moreover, thoracic anaesthesia usually requires highly complex airway management procedures because of the need for one-lung isolation and one-lung ventilation. Therefore, in the current pandemic, providing a fast-track algorithm for scientifically standardized diagnostic criteria and treatment recommendations for patients with lung cancer is urgent. Suggestions for improving existing contagion control guidelines are needed, even in the case of non-symptomatic patients who possibly are responsible for virus spread. A COVID-19-specific intraoperative management strategy designed to reduce risk of infection in both health care workers and patients is also required.

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Care of patients with pulmonary arterial hypertension during the coronavirus (COVID-19) pandemic

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The COVID-19 pandemic presents many unique challenges when caring for patients with pulmonary hypertension. The COVID-19 pandemic has altered routine standard of care practice and the acute management particularly for those patients with pulmonary arterial hypertension, where pulmonary arterial hypertension-specific treatments are used. It is important to balance the ongoing care and evaluation of pulmonary arterial hypertension patients with “exposure risk” to COVID-19 for patients coming to clinic or the hospital. If there is a morbidity and mortality benefit from starting pulmonary arterial hypertension therapies, for example in a patient with high-likelihood of pulmonary arterial hypertension, then it remains important to complete the thorough evaluation. However, the COVID-19 outbreak may also represent a unique time when pulmonary hypertension experts have to weigh the risks and benefits of the diagnostic work-up including potential exposure to COVID-19 versus initiating targeted pulmonary arterial hypertension therapy in a select high-risk, high likelihood World Symposium Pulmonary Hypertension Group 1 pulmonary arterial hypertension patients. This document will highlight some of the issues facing providers, patients, and the pulmonary arterial hypertension community in real-time as the COVID-19 pandemic is evolving and is intended to share expected common clinical scenarios and best clinical practices to help the community at-large.

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Management of transplant patients outside hospital during COVID-19 epidemic: A Chinese experience

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Coronavirus disease 2019 (COVID-19) pandemic poses an increasing challenge for transplant community. Aggressive management measures are conductive to improve compliance and to lower the risk of intra-hospital infection. In this Personal Viewpoint essay, we shared experiences about management strategies of transplant patients outside hospital amid the epidemic. With the aid of Cloud Clinic service and telemedicine care, transplant patients could be regularly followed up and get medical consultation online. Furthermore, personal health education and mental health assistance are enrolled in our practice.

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Consensus Statement on Coronary Intervention during the Coronavirus Disease 2019 (COVID-19) Pandemic: from the Korean Society of Interventional Cardiology (KSIC)

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Coronavirus disease 2019 (COVID-19) is a highly contagious disease caused by the novel virus severe acute respiratory syndrome coronavirus-2. The first case developed in December, 2019 in Wuhan, China; several months later, COVID-19 has become pandemic, and there is no end in sight. This disaster is also causing serious health problems in the area of cardiovascular intervention. In response, the Korean Society of Interventional Cardiology formed a COVID-19 task force to develop practice guidelines. This special article introduces clinical practice guidelines to prevent secondary transmission of COVID-19 within facilities; the guidelines were developed to protect patients and healthcare workers from this highly contagious virus. We hope these guidelines help healthcare workers and cardiovascular disease patients around the world cope with the COVID-19 pandemic.

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Lessons Learned and Experiences Shared From the Front Lines: Milan and Madrid.

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Under the aegis of the American College of Surgeons (ACS), the senior author (SDW), a member of the Board of Regents of the ACS, interviewed 3 of his international colleagues in colon and rectal surgery who found themselves dealing with a flood of patients from the COVID-19 pandemic. Each was in a "hot spot" where the outbreak overwhelmed the capacities of the hospitals. Professor Antonino Spinelli of Milan dealt with the sudden increase in COVID-19 patients that threatened to push all other emergencies and urgent cancer cases aside. Providers lacked the personal protective equipment to be adequately safe in the environment. In Madrid, Dr Julio Mayol recounted how 10%-15% of the workers in his hospital were incapacitated by the virus, many of them doctors providing direct care to patients. The disease is so prevalent that all emergency patients are treated as though they have the infection. Having practices in Saudi Arabia and Spain, Dr Delia Cortés-Guiral saw how the former country controlled the epidemic through a strict lockdown of travel and closure of holy pilgrimage sites and social gatherings. In contrast, upon her return to her native country, she experienced the near-breakdown of the health care system by the suddenness of the outbreak. "There are now no specialists now, she says." All of the specialties are treating COVID-19 patients and all of us are learning at the same time how to deal with this disease."It is a nightmare now here in Spain".

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Home Care for Cancer Patients During COVID-19 Pandemic: The Double Triage Protocol

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Abstract Patients with cancer have an increased risk of developing severe forms of coronavirus disease 2019, and patients with advanced cancer who are followed at home represent a particularly frail population. Although with substantial differences, the challenges that cancer care professionals have to face during a pandemic are quite similar to those posed by natural disasters. We have already managed the oncological home care service in L’Aquila (middle Italy) after the 2009 earthquake. With this letter, we want to share the procedures and tools that we have started using at the home care service of the Tuscany Tumor Association during the coronavirus disease 2019 pandemic.

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Recommendations for Safe Dental Care: A Systematic Review of Clinical Practice Guidelines in the First Year of the COVID-19 Pandemic

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In the context of a pandemic, the rapid development of clinical practice guidelines (CPGs) is critical to guide dental staff towards the safe provision of dental care; detailed knowledge of the recommendations will help to achieve the intended results. We carried out a systematic review of the recommendations in clinical practice guidelines (CPGs) on the provision of dental care issued during the first year of the COVID-19 pandemic. A systematic database search was performed in MEDLINE, EMBASE, LILACS, Epistemonikos, and Trip databases to identify documents with recommendations intended to minimize the risk of COVID-19 transmission during dental care. The selection process and data extraction were carried out by two researchers independently. The majority of CPGs recommended the use of rubber dam, high-volume evacuator, mouthwash prior to dental care, four-handed work, and mechanical barriers. The use of aerosol-generating equipment should be avoided whenever possible. In aerosol-generating procedures, the use of a N95 respirator (or similar) is recommended, in addition to a face protector, an impermeable disposable apron/gown, a cap, and gloves. The CPGs developed during the first year of the pandemic offer recommendations which guide dental staff in providing safe dental care, minimizing exposure to SARS-CoV-2 and reducing the risk of COVID-19 infection in the clinical environment. Such recommendations must, however, be updated as new evidence arises.

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Please summerize the given abstract to a title

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78,356

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234,658

Cardiothoracic Surgery during COVID-19: Our Experience with Different Strategies

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BACKGROUND: An acute respiratory disease (COVID-19), caused by a novel coronavirus (SARS-CoV-2,), has been declared a pandemic by WHO. A surgery on COVID-19 patients not only involves a risk of spread of the disease but also there is a serious concern for the patient's surgical outcomes and resources requirement. AIM: The retrospective study is aimed to provide a protocol for pre-operative testing of SARS CoV-2 using RT-PCR in the patient undergoing cardio-thoracic surgeries. MATERIAL AND METHODS: To analyze the impact of pre-operative testing of SARS- CoV-2 using RT-PCR in the patient undergoing elective cardio-thoracic surgeries. The patient who underwent surgical interventions during the COVID-19 lockdown period was divided into two phases. Phase I (without COVID-19 RT-PCR testing) and Phase II (with pre-operative COVID-19 RT-PCR testing). The retrospective comparison between the two study groups was done using Student t-test, Mann–Whitney U, and Chi square (χ(2)) test depending upon the clinical variable to be analyzed. RESULTS: During the early phase (phase I), 26 patients underwent cardio-thoracic surgery without COVID-19 RT-PCR test. Whereas, during phase II, all patients were tested for COVID-19 using RT-PCR, preoperatively and a total of 64 surgeries were performed during this phase. One patient planned for CABG was positive on RT-PCR for COVID-19 and was sent to the quarantine ward. The difference in the pre-operative hospital stay between two groups was found to be statistically significant and a significant decrease in the number of PPE kits used, during the phase I. CONCLUSION: All asymptomatic patients should be tested for COVID-19 using RT-PCR prior to cardio-thoracic surgeries not only to contain the disease but to avoid potential implications of COVID-19 on the perioperative course, without added financial implications.

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234,660

Please summerize the given abstract to a title

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78,367

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234,691

Solid organ transplantation in the era of COVID-19: lessons from the past six months

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COVID-19 outbreak has significantly upended solid organ transplant (SOT) practice around the world. Early reports confirmed the heavy burden of COVID-19 in SOT recipients with mortality rates reaching up to 35%. Because most transplant recipients harbored multiple comorbidities known to be associated with a severe course of COVID-19, the true impact of immunosuppression by itself remained an unsolved issue. Transplant societies have initially recommended to postpone non urgent renal transplantations, while trying to maintain life-saving transplant programs, such as heart, lung and liver transplantations. The pandemic thus resulted in an unprecedented and sudden drop of transplant activity worldwide. Moreover, the best treatment strategy in infected patients was challenging. Both reduction of immunosuppression and use of targeted therapies aiming at counteracting SARS-CoV-2 infection were the two faces of the therapeutic armamentarium. Recent controlled studies have better delineated the basis of mitigating and management strategies to improve patients' outcome. Nevertheless, and given the persistence of circulating virus, evidence-based recommendations in SOT recipients remain unclear. The resumption of transplant activity should be tailored with careful selection of both donors and recipients. Transplant decision should be made on a case-by-case basis after thorough assessment of the risks and benefits.

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78,367

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234,693

Please summerize the given abstract to a title

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78,385

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234,745

Thoracic Surgeons’ Insights: Improving Thoracic Surgery Outcomes During the Coronavirus Disease 2019 Pandemic

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[Figure: see text]

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234,747

Please summerize the given abstract to a title

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78,414

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234,832

Clinical strategies for optimizing infusion center care through a pandemic.

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1

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234,833

The national pandemic resulting from the novel coronavirus, COVID-19, has made the delivery of care for patients with cancer a challenge. There are competing risks of mortality from cancer versus serious complications and higher risk of death from COVID-19 in immunocompromised hosts. Furthermore, compounding these concerns is the inadequate supply of personal protective equipment, decreased hospital capacity, and paucity of effective treatments or vaccines to date for COVID-19. Guidance measures and recommendations have been published by national organizations aiming to facilitate the delivery of care in a safe and effective manner, many of which, are permanently adoptable interventions. Given the critical importance to continue chemotherapy, there remains additional interventions to further enhance patient safety while conserving healthcare resources such as adjustments in medication administration, reduction in laboratory or drug monitoring, and home delivery of specialty infusions. In this manuscript, we outline how to implement these actionable interventions of chemotherapy and supportive care delivery to further enhance the current precautionary measures while maintaining safe and effective patient care. Coupled with current published standards, these strategies can help alleviate the numerous challenges associated with this pandemic.

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235,240

Mount Sinai NY Surgeon on the Front Lines of the COVID-19 Pandemic in Brooklyn, NY, USA.

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A surgeon was among the teams caring for critically-ill patients with COVID-19 infection during the height of the pandemic in March and April 2020 in Brooklyn. He recorded his experiences and thoughts as events unfolded, a chronicle of the landmark public health event of the century. Working to exhaustion alongside his colleagues from Mount Sinai Hospital, he encountered tragedy and inspiration.

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78,588

92

235,354

Increased photokeratitis during the coronavirus disease 2019 pandemic: Clinical and epidemiological features and preventive measures

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An increased incidence of photokeratitis has occurred during the coronavirus disease 2019 (COVID-19) pandemic due to improper and unprotected use of ultraviolet lamps. Here, we summarize the clinical and epidemiological features of this increased incidence of photokeratitis and share advice in using health education to prevent it. We collected data from patients diagnosed with photokeratitis from October 7, 2019 to December 1, 2019, and from February 17, 2020 to April 12, 2020, and compared the frequency of onset, site of ultraviolet radiation (UVR) exposure, reason for exposure, exposure time, and recovery time. We also implemented and evaluated multiple measures of public health education to prevent increased disease. After the COVID-19 outbreak, the frequency of onset of photokeratitis increased significantly, especially among young women. The main reason for UVR exposure changed from welding to disinfection. The incidence sites varied, and the exposure time was longer. As a result, patients needed a longer time to recover. Positive health education was an useful and convenient measure to prevent the disease. While the COVID-19 pandemic is ongoing, more attention should be paid to public health and implement positive measures to prevent photokeratitis.

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78,718

92

235,744

New Vision for a Patient with Diabetes and Retinal Migraines

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Retinal migraine is a chronic, disabling headache disorder that strikes sufferers with recurrent, transient episodes of monocular vision loss before the onset of a throbbing headache on the same side as the visual disturbance The author discusses the experience of a patient with type 2 diabetes perceiving these frightening episodes of transient visual disturbances during the coronavirus disease 2019 pandemic in which stressors and missed meals precipitated and exacerbated these attacks With an increased understanding of the characteristics of retinal migraines, nurse practitioners can work closely with other health care professionals to provide comprehensive and patient-centered care to these individuals

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78,748

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235,834

Pandemics and Pediatric Otolaryngology

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OBJECTIVE: To describe how the COVID pandemic changed the epidemiology and management of pediatric otolaryngologic diseases, which may influence clinical decision-making in the future. FINDINGS: Many changes were made to the structure of healthcare delivery to minimize transmission of coronavirus. As a result, there was a widespread adoption of telehealth. Additionally, guidelines were published with new protocols for evaluation and management of common pediatric otolaryngologic conditions, which in many circumstances, delayed or replaced surgical intervention. Now, as we evaluate the impact of these clinical changes, we have gained new understanding about the pathophysiology of certain pediatric conditions, namely otitis media, for which upper respiratory infection (URI) exposure may play a larger role than previously thought. CONCLUSION: As we have altered practice patterns for common pediatric otolaryngologic conditions, we recognize that ongoing research may help us determine if surgical interventions have been overutilized in the past and help guide clinical practice guidelines moving forward.

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235,960

Problems of care for STEMI patients in coronavirus pandemic

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235,961

The covid-19 pandemic negatively affects time-dependent care and the course of STEMI in several aspects: Some patients delay seeking emergency care or even do not call it at all because of fear of contracting covid-19 at hospitals. The presentations of STEMI and covid-19 can overlap and mimic each other. Both conditions may coexist. Uncertainty regarding diagnosis may add to delays. Provider΄s concerns about the covid-19 infection or lack of cath lab staff may lead to changes in treatment algorhithms. There may also be delay due to the infection-control measures employed by medical staff. Reduction in non-covid care, overwhelmed emergency medical services and hospitals, staff-absences, and lack of beds may all lead to treatment delay or even inability to provide it. Inflammatory and prothrombotic states in patients with covid-19 increase the risk of developing STEMI as well as that of STEMI complications. Hypoxia due to covid-19 lung disease deepens myocardial ischemia during STEMI and may extend the volume of STEMI and increase the risk of heart failure. Covid myocarditis Conclusion: It is apparent that STEMI in covid-19 infected patients is not the same disease process as STEMI that without covid-19 infection. Patients with STEMI and covid-19 have a higher risk of heart failure, cardiac arrest, cardiogenic shock, greater intracoronary thrombosis and stent thrombosis, resulting in higher cardiac and non-cardiac mortality. Aggressive antithrombotic treatment is recommended. Even in the covid era it is essential to insist on timely treatment of STEMI. Training of cardiac catheterization personnel on how to use personal protective equipment as well as vaccination are crucial to limit the risk of acquiring infection. (English) [ABSTRACT FROM AUTHOR] Infekce covid-19 a covidová pandemie představují problém pro péči o nemocné se STEMI. Výskyt, průběh, léčbu a prognózu STEMI ovlivňuje covidová epidemie v několika aspektech: Část nemocných z obavy před covidovou nákazou v nemocnici oddaluje přivolání zdravotnické pomoci, nebo dokonce pomoc vůbec nezavolá. Příznaky STEMI a covid-19 se mohou překrývat a vzájemně napodobovat, navíc mohou koexistovat, nejistota při stanovení diagnózy může vést ke zpoždění léčby. Obava z covidové nákazy zdravotníků nebo nedostatek personálu katetrizačních laboratoří může vést ke změně léčebných algoritmů. Přetížené zdravotní služby, omezení „necovidové“ péče, chybějící personál, nedostatek lůžek mohou mít za následek prodlevu v léčbě STEMI až nemožnost léčbu poskytnout. Použítí ochranných prostředků proti šíření covid-19 může vést ke zpoždění léčby. Zánětlivý a protrombotický stav během covidové infekce zvyšuje riziko vzniku infarktu myokardu a zvyšuje riziko trombotických komplikací již probíhajícího STEMI. Hypoxie způsobená covidovým postižením plic prohlubuje ischemii myokardu při AIM, může zvětšit rozsah infarktu a zvyšuje riziko srdečního selhání při AIM. Covidová myokarditida. Závěr: STEMI u nemocného s covid-19 není stejná nemoc jako STEMI bez covid-19. Nemocní s covid-19 a STEMI mají častěji srdeční selhání a srdeční zástavu, rozsáhlejší intrakoronární trombózu, významně vyšší riziko akutní trombózy stentu, kardiogenního šoku po PCI a významně vyšší nemocniční kardiální i nekardiální mortalitu. Je indikována agresivnější antitrombotická léčba. I v covidové době je nutná maximální snaha o co nejrychlejší zajištění reperfuzní léčby a dodržení časových limitů pro její provedení. Velmi důležité jsou nácvik používání ochranných pomůcek proti šíření infekce a vakcinace. (Czech) [ABSTRACT FROM AUTHOR] Copyright of Intervencní a Akutní Kardiologie is the property of SOLEN sro and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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79,136

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236,998

Contradictory Responses to the COVID-19 Pandemic in Amyotrophic Lateral Sclerosis Patients and Their Families and Caregivers in Japan

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Objective The coronavirus disease 2019 (COVID-19) pandemic has resulted in a shortage of medical resources, including ventilators, personal protective equipment, medical staff, and hospital beds. We investigated the impact of COVID-19 in amyotrophic lateral sclerosis (ALS) patients, their families, caregivers, and medical experts. Methods We conducted a nationwide ALS webinar about COVID-19 in May 2020 and sent a questionnaire to those enrolled. Results A total of 135 participants (31 ALS patients; 23 families and caregivers of ALS patients; 81 medical experts) responded to this cross-sectional self-report questionnaire. The results showed that tracheostomy and invasive ventilation (TIV) was used in 22.6% of ALS patients, whereas 77.4% of ALS patients were not under TIV. Among non-TIV patients (n=24), 79.2% did not want TIV in the future. However, 47.4% of non-TIV patients not wanting a tracheostomy in advanced stages replied that they would want an emergency tracheostomy if they developed COVID-19-related pneumonia. These results suggest that ALS patients may be receptive to emergency treatments for reasons other than ALS. In addition, approximately half of the ALS patients agreed with the policy of not ventilating the elderly or ALS patients in case of a ventilator shortage. Furthermore, compared with medical experts, few ALS patients reported that the chance for ALS patients to obtain work was higher due to the increasing availability of remote work. Conclusions This survey indicates that the COVID-19 pandemic might be associated with increased distress about access to care and work, inducing contradictory responses and potential hopelessness among ALS patients.

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79,137

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Enteral stoma care during COVID‐19 pandemic: practical advice

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The COVID‐19 pandemic represents an enormous challenge for global health systems. Stoma care represents a potentially neglected component during the outbreak and no specific recommendations on stoma care have been published up till now. In this manuscript, MISSTO (Multidisciplinary Italian Study group for STOmas) provides practical advice on optimal enteral stoma care in adults during the COVID‐19 pandemic. Translations in four other languages (Spanish, Italian, Traditional Chinese, Simplified Chinese) are attached in the appendix to enable dissemination of the document worldwide.

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Evidence-based management of COVID-19 in cancer patients: Guideline by the Infectious Diseases Working Party (AGIHO) of the German Society for Haematology and Medical Oncology (DGHO)

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Since its first detection in China in late 2019 the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the associated infectious disease COVID-19 continue to have a major impact on global healthcare and clinical practice. Cancer patients, in particular those with haematological malignancies, seem to be at an increased risk for a severe course of infection. Deliberations to avoid or defer potentially immunosuppressive therapies in these patients need to be balanced against the overarching goal of providing optimal antineoplastic treatment. This poses a unique challenge to treating physicians. This guideline provides evidence-based recommendations regarding prevention, diagnostics and treatment of SARS-CoV-2 infection and COVID-19 as well as strategies towards safe antineoplastic care during the COVID-19 pandemic. It was prepared by the Infectious Diseases Working Party (AGIHO) of the German Society for Haematology and Medical Oncology (DGHO) by critically reviewing the currently available data on SARS-CoV-2 and COVID-19 in cancer patients applying evidence-based medicine criteria.

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Safety guidelines for non-surgical facial procedures during covid-19 outbreak

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BACKGROUND: The novel coronavirus (COVID-19) pandemic is expected to last for an extended time, making strict safety precautions for office procedures unavoidable. The lockdown is going to be lifted in many areas, and strict guidelines detailing the infection control measures for aesthetic clinics are going to be of particular importance. METHODS: A virtual meeting was conducted with the members (n=12) of the European Academy of Facial Plastic Surgery Focus Group to outline the safety protocol for the non-surgical facial aesthetic procedures for aesthetic practices in order to protect the clinic staff and the patients from SARS-CoV-2 infection. The data analysis was undertaken by thematic and iterative approach. RESULTS: Consensus guidelines for non-surgical facial aesthetic procedures based on current knowledge are provided for three levels: precautions before visiting the clinic, precautions during the clinic visit, and precautions after the clinic visit. CONCLUSIONS: Sound infection control measures are mandatory for non-surgical aesthetic practices all around the world. These may vary from country to country, but this logical approach can be customized according to the respective country laws and guidelines.

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79,235

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Our experiences of resuming services in ENT departments in Wuhan, once a COVID-19 epicenter

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Abstract The pandemic of coronavirus disease 2019 (COVID-19) showed a significant impact on routine daily services in departments of otorhinolaryngology head and neck surgery. The city of Wuhan, as the first reported epicenter in the world, resumed medical service since April 8, 2020. As the biggest ENT services provider in Wuhan, we share out institution's triage and screening system in the resuming period.

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79,263

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Datasets:

AdapterOcean
/

med_alpaca_standardized_cluster_92_std

Dataset Card for "med_alpaca_standardized_cluster_92_std"